Von Willebrand Disease

The von Willebrand disease (VWD) is a congenital coagulopathy that represents the most common hereditary hemorrhagic syndrome in humans (1-2% of the general population). The International Society on Thrombosis and Haemostasis's (ISTH) classification is based on the definition of qualitative and quantitative defects of von Willebrand factor (VWF). This genetic disorder is transmitted as an autosomal dominant or, less frequently, recessive and prevents platelet adhesion and a correct blood clotting.